Lovastatin-induced acute rhabdomyolysis.
نویسندگان
چکیده
Severe rhabdomyolysis complicated by respiratory and renal failure developed three weeks after initiation of low dose lovastatin therapy in a 79 year old, non-immunocompromised patient. The concomitant use of gemfibrozil may increase the risk of this complication.
منابع مشابه
Rhabdomyolysis secondary to lovastatin therapy.
We report a case of lovastatin-induced rhabdomyolysis and resulting life-threatening renal failure. Lovastatin, a hypocholesterolemic agent, decreases endogenous cholesterol synthesis by inhibiting 3-hydroxy-3-methylglutaryl coenzyme A reductase (EC 1.1.1.88). This agent has been implicated in causing rare serious side effects in various clinical settings; however, the mechanism of these advers...
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Assistant Professor C CHRYSANTHOPOULOS (Patras Medical School, Patras, Greece) and Professor NICHOLAS KOUNIS (Patras Technological Educational Institute, Patras 26221, Greece) write: We report two cases in which rhabdomyolysis occurred after combined treatment with lovastatin and cholestyramine. Case I-A 31 year old male athlete with type Ila hyperlipidaemia was treated with lovastatin 20 mg tw...
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ورودعنوان ژورنال:
- Postgraduate medical journal
دوره 66 774 شماره
صفحات -
تاریخ انتشار 1990